Description

2-Ethynyloxane is a specialized organic compound featuring an oxane (tetrahydropyran) ring substituted with an ethynyl group, offering a unique combination of cyclic ether stability and alkyne reactivity. This structural motif makes it a valuable building block and intermediate in advanced synthetic chemistry. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for introducing alkyne handles for click chemistry or further functionalization.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators where the oxane ring can contribute to bioavailability and stability.
• Ligand and Catalyst Development: Acts as a precursor for creating specialized ligands in transition metal catalysis, leveraging the alkyne group for coordination or tethering.
• Material Science Monomer: Employed in polymer and advanced material research to incorporate cyclic ether and alkyne functionalities into polymer backbones or as cross-linking agents.
• Organic Synthesis Building Block: Provides a versatile scaffold for heterocyclic and natural product synthesis, enabling diverse chemical transformations.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags due to the bio-orthogonal reactivity of the alkyne group.

Basic Information

Product Name	2-Ethynyloxane
CAS No.	76928-53-5
Molecular Formula	C7H10O
Molecular Weight	110.15 g/mol
Synonyms	2-Ethynyltetrahydro-2H-pyran; 2-Ethynyltetrahydropyran; 2-Ethynyloxacyclohexane; Oxane, 2-ethynyl-; 2-Ethynyloxycyclohexane; 2-(Ethynyl)oxane; 76928-53-5
EINECS	Contact for details

Quality Control

Our 2-Ethynyloxane is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatography (GC/HPLC) and spectroscopic methods (NMR, IR), to ensure high purity and consistency. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request. We are committed to meeting the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to the presence of the alkyne moiety, it is recommended to store under an inert atmosphere for long-term stability and to minimize potential oxidation or polymerization. Keep away from strong oxidizers and acids.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.