Description

n-[4-(1,1,1,3,3,3-Hexafluoro-2-Hydroxypropan-2-Yl)Phenyl]Benzenesulfonamide is a high-value, fluorinated sulfonamide derivative characterized by its unique hexafluoroisopropanol-substituted aromatic structure. This compound matters as a critical advanced pharmaceutical intermediate and specialty chemical building block, enabling the synthesis of complex molecules with enhanced properties. It is primarily needed by R&D and production teams in the pharmaceutical, agrochemical, and advanced materials sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in areas requiring fluorinated motifs for improved metabolic stability and bioavailability.
• Agrochemical Research: Used in developing advanced herbicides, fungicides, and pesticides where the sulfonamide and fluorinated groups contribute to biological activity and environmental persistence.
• Material Science: Serves as a monomer or additive in the production of specialty polymers, coatings, and resins to impart unique surface properties, chemical resistance, or optical characteristics.
• Liquid Crystal & OLED Materials: Potential precursor for electronic chemicals used in display technologies due to its rigid, polarizable aromatic structure and fluorine content.
• Chemical Synthesis Reagent: Employed in organic synthesis as a protecting group, catalyst, or ligand in transition metal catalysis, leveraging the sulfonamide functionality.
• Academic & Industrial R&D: Serves as a reference standard and research chemical for investigating structure-activity relationships (SAR) and new synthetic methodologies.

Basic Information

Product Name	n-[4-(1,1,1,3,3,3-Hexafluoro-2-Hydroxypropan-2-Yl)Phenyl]Benzenesulfonamide
CAS No.	76856-51-4
Molecular Formula	C15H12F6NO3S
Molecular Weight	400.32 g/mol
Synonyms	Benzenesulfonamide, N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxy-2-propyl)phenyl]-; 4-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)-N-phenylbenzenesulfonamide; N-[4-(Hexafluoro-2-hydroxyisopropyl)phenyl]benzenesulfonamide; 2-(4-(Phenylsulfonamido)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol; HFS; Contact for additional trade names and abbreviations.
EINECS	Contact for details

Quality Control

Our n-[4-(1,1,1,3,3,3-Hexafluoro-2-Hydroxypropan-2-Yl)Phenyl]Benzenesulfonamide is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids/bases and incompatible materials. The product may be hygroscopic; handle and store under dry conditions to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.