Description

5-Amino-N,N'-Bis(2,3-Dihydroxypropyl)-2,4,6-Triiodo-1,3-Benzenedicarboxamide Tetraacetate is a high-purity, non-ionic iodinated organic compound primarily utilized as a key intermediate in the synthesis of advanced X-ray contrast media. Its molecular structure is engineered for enhanced water solubility and biocompatibility, making it a critical building block for diagnostic imaging agents. This compound is essential for manufacturers in the pharmaceutical and fine chemical sectors who require reliable, high-quality raw materials for producing next-generation contrast agents.

Application

• Pharmaceutical Intermediate: Primary use as a precursor in the synthesis of non-ionic, low-osmolar X-ray and CT scan contrast media.
• Diagnostic Imaging Agent Synthesis: A crucial building block for iodinated contrast agents like iopamidol, iohexol, and other triiodobenzene derivatives.
• Research & Development: Used in biochemical and pharmacological research for developing novel diagnostic compounds and studying contrast agent mechanisms.
• Fine Chemical Manufacturing: Serves as a specialized intermediate for creating complex, high-value iodinated aromatic compounds.
• Radiology Product Development: Integral to formulating new, safer, and more efficient contrast media with improved patient tolerance profiles.

Basic Information

Product Name	5-Amino-N,N'-Bis(2,3-Dihydroxypropyl)-2,4,6-Triiodo-1,3-Benzenedicarboxamide Tetraacetate
CAS No.	76801-94-0
Molecular Formula	C22H28I3N3O12
Molecular Weight	899.18 g/mol
Synonyms	5-Amino-2,4,6-triiodo-N,N'-bis(2,3-dihydroxypropyl)isophthalamide tetraacetate; Iopamidol Impurity; Iopamidol Intermediate; Iohexol Related Compound; 5-Amino-2,4,6-triiodoisophthalamide derivative; Non-ionic contrast media intermediate; Triiodobenzenedicarboxamide derivative; AJI 92
EINECS	Contact for details

Quality Control

Our 5-Amino-N,N'-Bis(2,3-Dihydroxypropyl)-2,4,6-Triiodo-1,3-Benzenedicarboxamide Tetraacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We adhere to cGMP principles where applicable to support our customers' regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.