Description

5-Amino-N,N'-Bis(2,3-Dihydroxypropyl)-2,4,6-Triiodo-1,3-Benzenedicarboxamide is a high-purity, non-ionic iodinated organic compound. It serves as a critical intermediate in the synthesis of advanced X-ray contrast media, valued for its excellent water solubility and low osmolality. This product is essential for pharmaceutical manufacturers and research institutions developing next-generation diagnostic imaging agents.

Application

• Primary intermediate in the synthesis of non-ionic iodinated X-ray contrast media (e.g., Iopromide, Ioversol).
• Key building block for research and development of novel diagnostic imaging agents.
• Used in the preparation of pharmaceutical active pharmaceutical ingredients (APIs) for computed tomography (CT) scans.
• Important raw material in specialty fine chemical synthesis requiring triiodinated benzene derivatives.

Basic Information

Product Name	5-Amino-N,N'-Bis(2,3-Dihydroxypropyl)-2,4,6-Triiodo-1,3-Benzenedicarboxamide
CAS No.	76801-93-9
Molecular Formula	C14H18I3N3O6
Molecular Weight	705.02 g/mol
Synonyms	5-Amino-2,4,6-triiodo-N,N'-bis(2,3-dihydroxypropyl)isophthalamide; Iopromide Intermediate; Ioversol Intermediate; 5-Amino-2,4,6-triiodo-N1,N3-bis(2,3-dihydroxypropyl)-1,3-benzenedicarboxamide; 76801-93-9; Non-ionic Contrast Media Intermediate; Triiodinated Isophthalamide Derivative
EINECS	Contact for details

Quality Control

Our production of 5-Amino-N,N'-Bis(2,3-Dihydroxypropyl)-2,4,6-Triiodo-1,3-Benzenedicarboxamide adheres to stringent quality management systems, ensuring batch-to-batch consistency and high purity suitable for pharmaceutical applications. All material is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with cGMP and ICH Q7 guidelines for active pharmaceutical ingredient intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.