Description

Boc-Tyr(Et)-Oh is a protected derivative of the amino acid tyrosine, specifically designed for use in peptide synthesis. This compound is critical for researchers and manufacturers who require precise control over chemical reactions to build complex peptide chains. It serves as a key building block for pharmaceutical R&D, particularly in the development of therapeutic peptides and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a protected tyrosine derivative, it is a fundamental reagent for the sequential assembly of peptides on resin supports.
• Solution-Phase Peptide Synthesis: Used in classical coupling reactions for constructing peptide fragments in solution.
• Pharmaceutical Intermediate: Serves as a crucial intermediate in the research and production of peptide-based active pharmaceutical ingredients (APIs).
• Bioconjugation and Labeling: The protected functional groups allow for selective modification, making it useful for creating labeled peptides for diagnostic or research purposes.
• Biochemical Research: Employed in academic and industrial laboratories for studying protein-protein interactions, enzyme substrates, and receptor ligands.
• Combinatorial Chemistry: Used in libraries for high-throughput screening to discover new bioactive peptide leads.

Basic Information

Product Name	Boc-Tyr(Et)-Oh
CAS No.	76757-91-0
Molecular Formula	C₁₆H₂₃NO₅
Molecular Weight	309.36 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-O-ethyl-L-tyrosine; Boc-O-Ethyl-L-tyrosine; Boc-L-Tyr(OEt)-OH; (2S)-2-[(2-Methylpropan-2-yl)oxycarbonylamino]-3-[4-(ethoxy)phenyl]propanoic acid; tert-Butoxycarbonyl-O-ethyl-L-tyrosine; Boc-Tyr(OEt)-OH; N-Boc-O-ethyl-L-tyrosine; Boc-Tyr(Et)-OH
EINECS	Contact for details

Quality Control

Our Boc-Tyr(Et)-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5%
Optical Rotation	-15.0° to -18.0° (c=1 in AcOH)
Chiral Purity	≥99.0% (L-isomer)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.