Description

n-Nitrosoglycocholic Acid is a chemically modified bile acid derivative, specifically the nitrosylated form of glycocholic acid. This compound is of significant interest in biochemical and pharmaceutical research due to its role as a potential intermediate or probe in studies related to bile acid metabolism and nitrosation processes. It serves as a critical reagent for researchers and developers in the life sciences sector, particularly those investigating liver function, digestive enzyme interactions, and specific metabolic pathways. The material is supplied with a focus on high purity and consistency to ensure reliable experimental outcomes.

Application

• Biochemical Research: Utilized as a specialized standard or reference compound in studies of bile acid chemistry and nitrosamine formation.
• Pharmaceutical Development: Acts as a key intermediate or building block in the synthesis of more complex molecules for drug discovery programs.
• Metabolic Pathway Analysis: Employed as a tool to investigate the metabolism and biological effects of nitrosated bile acids in in vitro and in vivo models.
• Analytical Chemistry: Serves as a high-purity calibration standard for analytical methods such as HPLC or LC-MS used in bioanalytical laboratories.
• Toxicology Studies: Used in research examining the formation and potential effects of N-nitroso compounds in biological systems.

Basic Information

Product Name	n-Nitrosoglycocholic Acid
CAS No.	76757-85-2
Molecular Formula	C26H42N2O7
Molecular Weight	494.63 g/mol
Synonyms	N-Nitroso-glycocholic Acid; Glycocholic Acid Nitroso Derivative; 3α,7α,12α-Trihydroxy-5β-cholan-24-oyl-N-nitrosoglycine; N-Nitroso-N-(3α,7α,12α-trihydroxy-24-oxo-5β-cholan-24-yl)glycine; Nitrosated Glycocholate
EINECS	Contact for details

Quality Control

Every batch of n-Nitrosoglycocholic Acid is produced and tested under stringent quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing key parameters such as assay purity and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.