Description

Insulin, (2-Nitro-4-Azidophenylacetyl)(B2)-Des-Phe(B1)- is a chemically modified insulin derivative, specifically engineered for advanced biochemical research and development. This compound is of significant value for its role as a photoaffinity labeling agent, enabling the study of insulin receptor interactions and binding sites. It is primarily needed by research institutions, pharmaceutical developers, and biotechnology companies engaged in metabolic disorder research, drug discovery, and proteomics.

Application

• Photoaffinity Labeling Studies: A critical tool for mapping the insulin receptor's active site and understanding ligand-receptor interactions at the molecular level.
• Biochemical Research: Used in fundamental research on insulin's mechanism of action, signal transduction pathways, and metabolic regulation.
• Pharmaceutical Development: Serves as a key intermediate or probe in the discovery and development of novel insulin analogs and diabetes therapeutics.
• Proteomics and Structural Biology: Employed to identify, isolate, and characterize insulin-binding proteins and complexes within biological systems.
• Diagnostic Reagent Development: Potential use in the development of advanced diagnostic assays for insulin-related disorders.

Basic Information

Product Name	Insulin, (2-Nitro-4-Azidophenylacetyl)(B2)-Des-Phe(B1)-
CAS No.	76688-14-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	NαB29-(2-Nitro-4-azidophenylacetyl)insulin B1-Des-phenylalanine; (2-Nitro-4-azidophenylacetyl)-Des-Phe(B1)-insulin; Insulin, NαB29-(2-nitro-4-azidobenzoyl)-B1-des-Phe; Photoaffinity Insulin Derivative; NAP-Insulin; 2-Nitro-4-azidophenylacetyl insulin analog; B1-Des-Phe Insulin Probe
EINECS	Contact for details

Quality Control

Our Insulin, (2-Nitro-4-Azidophenylacetyl)(B2)-Des-Phe(B1)- is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Quality is verified through advanced analytical techniques including HPLC and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each batch to support your research and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to moisture, heat, or light will compromise stability and activity. Allow the vial to equilibrate to room temperature before opening to minimize condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Biological Activity	Assessed by receptor binding assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.