Description

Cefbuperazone Sodium CAS NO 76648-01-6 is a semi-synthetic, broad-spectrum cephalosporin antibiotic belonging to the cephamycin class. This compound is valued for its enhanced stability against β-lactamases, making it effective against a wide range of Gram-positive and Gram-negative bacteria. It is primarily utilized in pharmaceutical research and development for the formulation of injectable antibiotic preparations.

Application

• Pharmaceutical Active Ingredient (API): Core component in the manufacture of injectable antibiotic formulations.
• Clinical Research: Used in studies investigating treatments for severe bacterial infections, including respiratory and intra-abdominal infections.
• Veterinary Medicine: Potential application in developing antibacterial treatments for livestock.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory testing in laboratories.
• Antimicrobial Susceptibility Testing: Used to prepare discs or solutions for in-vitro antibiotic efficacy testing.

Basic Information

Item	Detail
Product Name	Cefbuperazone Sodium
CAS No.	76648-01-6
Molecular Formula	C22H21N9NaO8S2
Molecular Weight	627.58 g/mol
Synonyms	Cefbuperazone Sodium Salt; BMY-25182; Sodium (6R,7S)-7-[[(2R)-2-[[4-Ethyl-2,3-dioxopiperazin-1-yl]carbonyl]amino]-2-phenylacetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate; Cefoperazone analog; T-1982
EINECS	Contact for details

Quality Control

Our Cefbuperazone Sodium is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identification by IR and NMR spectroscopy, and stringent tests for related substances and residual solvents. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure compliance with pharmaceutical-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
pH (10% solution)	4.5 - 6.5
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Bacterial Endotoxins	< 0.10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.