Description

Cefbuperazone CAS NO 76610-84-9 is a second-generation cephalosporin antibiotic belonging to the cephamycin class, characterized by its broad-spectrum activity against both gram-positive and gram-negative bacteria. Its primary value lies in its enhanced stability against β-lactamases, making it a critical intermediate in the synthesis of advanced pharmaceutical formulations. This compound is essential for manufacturers and research institutions in the pharmaceutical and biotechnology sectors developing injectable antibiotic treatments.

Application

• Pharmaceutical Active Ingredient (API): Core intermediate in the synthesis of finished antibiotic dosage forms.
• Antibacterial Drug Development: Used in R&D for creating new or improved cephalosporin-based therapies.
• Veterinary Medicine: Formulation of broad-spectrum antibacterial treatments for animal health.
• Clinical Research: Serves as a reference standard in pharmacokinetic and pharmacodynamic studies.
• Microbiological Studies: Used in laboratories to study bacterial resistance mechanisms and antibiotic efficacy.

Basic Information

Product Name	Cefbuperazone
CAS No.	76610-84-9
Molecular Formula	C22H22N8O8S2
Molecular Weight	590.59 g/mol
Synonyms	Cefbuperazone; Cefoperazone analog; T-1982; (6R,7R)-7-[[(2R)-2-[[(4-Ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino]-2-phenylacetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; 7-[D(-)-α-(4-Ethyl-2,3-dioxo-1-piperazinylcarbonylamino)-α-phenylacetamido]-3-(1-methyl-1H-tetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our Cefbuperazone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identification by IR and NMR spectroscopy, and stringent control of related substances and residual solvents. Certificates of Analysis (COA) documenting compliance with in-house pharmaceutical-grade specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept in a dry environment and opened under low-humidity conditions when necessary.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.