Description

Suc-Arg-Pro-Phe-His-Leu-Leu-Val-Tyr-Amc Tfa is a fluorogenic peptide substrate designed for the sensitive detection and quantification of protease activity. This compound matters as a critical research tool in enzymology and drug discovery, enabling precise biochemical assays. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on developing therapeutic agents targeting specific proteolytic pathways.

Application

• Protease Enzyme Assays: Used as a specific fluorogenic substrate for measuring the activity of various proteases in high-throughput screening (HTS) platforms.
• Drug Discovery & Development: Essential for identifying and characterizing novel protease inhibitors as potential therapeutic candidates.
• Biochemical Research: Facilitates kinetic studies and mechanistic analysis of enzyme-substrate interactions in purified systems.
• Diagnostic Reagent Development: Serves as a key component in developing sensitive diagnostic kits for detecting abnormal protease levels linked to diseases.
• Cell Biology Studies: Employed to monitor protease activity within cellular and tissue extracts to understand physiological and pathological processes.

Basic Information

Product Name	Suc-Arg-Pro-Phe-His-Leu-Leu-Val-Tyr-Amc Tfa
CAS No.	76524-84-0
Molecular Formula	C58H81N15O14 • C2HF3O2
Molecular Weight	Contact for details
Synonyms	Suc-Arg-Pro-Phe-His-Leu-Leu-Val-Tyr-AMC TFA; Suc-RPFHLLVY-AMC TFA; N-Succinyl-Arg-Pro-Phe-His-Leu-Leu-Val-Tyr-7-Amido-4-Methylcoumarin Trifluoroacetate; Fluorogenic Substrate for Proteases; Suc-R-P-F-H-L-L-V-Y-AMC TFA; Protease Substrate 76524-84-0
EINECS	Contact for details

Quality Control

Our Suc-Arg-Pro-Phe-His-Leu-Leu-Val-Tyr-Amc Tfa is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for critical research applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.