Description

Oxiconazole Related Compound A (20 Mg) (2',4'-Dichloro-2-Imidazol-1-Ylacetophenone (E)-[o-(2,4-Dichlorobenzyl)Oxime]) is a high-purity chemical reference standard essential for analytical and research purposes. This compound is critical for ensuring the quality, safety, and efficacy of pharmaceutical products by serving as a key impurity marker for the antifungal agent Oxiconazole. It is primarily required by pharmaceutical R&D laboratories, quality control (QC) departments, and analytical service providers engaged in method development, validation, and regulatory compliance.

Application

• Pharmaceutical Impurity Profiling and Control: Used as a certified reference material (CRM) for the identification and quantification of specified impurities in Oxiconazole API and finished drug products.
• Analytical Method Development and Validation: Serves as a critical standard for developing and validating HPLC, UPLC, or GC methods in compliance with ICH Q2(R1) and other regulatory guidelines.
• Stability Studies: Employed to monitor the formation of degradation products in Oxiconazole formulations under various stress conditions.
• Pharmacopoeial Testing: Supports testing procedures as per USP, EP, or other pharmacopoeial monographs for Oxiconazole.
• Regulatory Submissions: Provides essential data for drug master files (DMFs), investigational new drug (IND) applications, and new drug applications (NDAs).
• Academic and Contract Research: Used in university and CRO settings for research on antifungal agents, metabolic pathways, and analytical chemistry.

Basic Information

Product Name	Oxiconazole Related Compound A (20 Mg) (2',4'-Dichloro-2-Imidazol-1-Ylacetophenone (E)-[o-(2,4-Dichlorobenzyl)Oxime])
CAS No.	76472-50-9
Molecular Formula	C18H14Cl2N2O2
Molecular Weight	361.22 g/mol
Synonyms	(E)-2',4'-Dichloro-2-(1H-imidazol-1-yl)acetophenone O-[(2,4-dichlorophenyl)methyl]oxime; Oxiconazole Impurity A; Oxiconazole EP Impurity A; Oxiconazole Related Substance A; (E)-[o-(2,4-Dichlorobenzyl)oxime] of 2',4'-Dichloro-2-imidazol-1-ylacetophenone; 1H-Imidazole, 1-[2-[(E)-[[(2,4-dichlorophenyl)methyl]oxy]imino]-2-(2,4-dichlorophenyl)ethyl]-
EINECS	Contact for details

Quality Control

This high-grade reference standard is produced and controlled under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity confirmation and structural verification by spectroscopic methods, to ensure it meets the exacting requirements for pharmaceutical impurity analysis. A detailed Certificate of Analysis (COA) is provided, which includes batch-specific data on identity, purity, and chromatographic profile.

Storage

Preserve in the original, tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccator or low-humidity environment to prevent moisture absorption. Handle with appropriate laboratory safety practices.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual unspecified impurity: ≤ 0.5% Total impurities: ≤ 2.0%
Water Content (KF)	≤ 1.0% w/w
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.