Description

Glycophorin is a crucial sialoglycoprotein primarily found in the membranes of red blood cells, playing a vital role in cell surface recognition and antigenic properties. Its significance lies in its use as a high-purity biochemical reagent and a critical research tool for studying membrane structure, glycobiology, and hematological disorders. This product is essential for researchers and manufacturers in the pharmaceutical, diagnostic, and life science research sectors, particularly for developing blood typing reagents, studying cellular interactions, and advancing glycoprotein-based therapeutics.

Application

• Biomedical Research: Used as a model glycoprotein for studying cell membrane architecture, glycoprotein functions, and carbohydrate-protein interactions.
• Diagnostic Reagent Production: Serves as a key antigenic component in the development and quality control of blood group serological typing reagents.
• Pharmaceutical Development: Employed in research for drug targeting and delivery systems that exploit specific cell surface receptors.
• Immunology Studies: Acts as a substrate or antigen in assays investigating immune responses, antibody binding, and autoimmune disease mechanisms.
• Cell Biology & Biochemistry: Utilized in lectin binding studies, electrophoresis standards, and as a marker for membrane protein purification protocols.
• Quality Control Standards: Functions as a reference standard in diagnostic kit manufacturing and laboratory proficiency testing.

Basic Information

Product Name	Glycophorin
CAS No.	76416-15-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Glycophorin A; PAS-1; Sialoglycoprotein; MN Sialoglycoprotein; Glycophorin from human erythrocytes; Erythrocyte glycophorin; Blood group MN glycoprotein; GPA; α-Sialoglycoprotein
EINECS	Contact for details

Quality Control

Our Glycophorin is produced and tested under stringent quality management systems to ensure batch-to-batch consistency and high biological activity. Each lot undergoes comprehensive analysis, including purity assessment via electrophoresis and verification of sialic acid content. A Certificate of Analysis (COA) detailing specific test results is provided with every shipment, ensuring compliance with research-grade specifications and supporting your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder or lyophilized solid
Identification (IR)	Conforms to reference standard
Purity (SDS-PAGE)	≥ 90% (Main Band)
Protein Content (Biuret)	≥ 85%
Sialic Acid Content	Contact for details
Solubility	Soluble in water or appropriate buffers
Biological Activity	Confirmed by hemagglutination inhibition or specific antibody binding

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.