Description

1-(1,2-Dioxopropyl)-S-Proline is a specialized chiral intermediate featuring a proline backbone modified with a dioxopropyl moiety. This compound matters for its role in the synthesis of complex, biologically active molecules, particularly in the development of pharmaceuticals and advanced agrochemicals. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for constructing novel compounds and exploring new synthetic pathways.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of potential drug candidates, especially protease inhibitors and other bioactive molecules.
• Agrochemical Research: Used in the development of novel, high-performance pesticides and herbicides with specific modes of action.
• Asymmetric Synthesis: Employed as a chiral auxiliary or precursor in stereoselective chemical reactions to induce desired optical activity.
• Fine Chemical Production: Serves as a precursor for the manufacture of complex specialty chemicals and advanced materials.
• Bioconjugation & Probe Development: Potential use in creating labeled compounds or probes for biochemical and diagnostic research.
• Academic & R&D Laboratories: Utilized in chemical research to explore new synthetic methodologies and reaction mechanisms.

Basic Information

Product Name	1-(1,2-Dioxopropyl)-S-Proline
CAS No.	76391-12-3
Molecular Formula	C8H11NO4
Molecular Weight	185.18 g/mol
Synonyms	(S)-1-(1,2-Dioxopropyl)pyrrolidine-2-carboxylic acid; S-Proline, 1-(1,2-dioxopropyl)-; 1-(1,2-Dioxopropyl)-L-proline; L-Proline, 1-(1,2-dioxopropyl)-; 1-(1,2-Dioxopropyl)-(S)-proline; 1-(1,2-Dioxopropyl)proline; 76391-12-3; Pyrrolidine-2-carboxylic acid, 1-(1,2-dioxopropyl)-, (S)-
EINECS	Contact for details

Quality Control

Our 1-(1,2-Dioxopropyl)-S-Proline is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.