Description

5-Methoxyacetylamino-2,4,6-Triiodoisophthalic Acid (2,3-Dihydroxypropyl)Amide Chloride is a high-purity, iodinated organic compound designed for advanced pharmaceutical synthesis. This compound matters as a critical intermediate in the development of modern X-ray contrast media, enabling precise imaging diagnostics. It is essential for research institutions and pharmaceutical manufacturers focused on creating next-generation non-ionic, low-osmolar contrast agents for enhanced patient safety and imaging clarity.

Application

• Primary Intermediate for synthesizing non-ionic X-ray contrast media (e.g., Iopamidol, Ioversol analogs).
• Research & Development of novel iodinated contrast agents with improved pharmacokinetic profiles.
• Pharmaceutical Manufacturing for active pharmaceutical ingredient (API) production under GMP guidelines.
• Preclinical Studies in diagnostic imaging research for computed tomography (CT).
• Chemical Reference Standard for quality control and analytical method development.

Basic Information

Product Name	5-Methoxyacetylamino-2,4,6-Triiodoisophthalic Acid (2,3-Dihydroxypropyl)Amide Chloride
CAS No.	76350-04-4
Molecular Formula	C15H17I3N2O7 • Cl
Molecular Weight	Contact for details
Synonyms	5-Methoxyacetamido-2,4,6-triiodoisophthaloyl chloride dihydroxypropylamide; Iopamidol Intermediate; Ioversol Related Compound; 5-Methoxyacetylamino-2,4,6-triiodo-N,N'-bis(2,3-dihydroxypropyl)isophthalamide chloride; 76350-04-4; Triiodoisophthalic acid derivative; Non-ionic contrast agent precursor
EINECS	Contact for details

Quality Control

Our 5-Methoxyacetylamino-2,4,6-Triiodoisophthalic Acid (2,3-Dihydroxypropyl)Amide Chloride is manufactured under strict quality systems suitable for pharmaceutical intermediate applications. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure compliance with stringent internal specifications. A comprehensive Certificate of Analysis (COA) detailing purity, related substances, and residual solvents is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.