Description

4-(4-Bromophenyl)-2-Methylbut-3-Yn-2-Ol CAS NO 76347-62-1 is a specialized organic intermediate featuring a brominated phenyl ring and a tertiary propargylic alcohol functional group. This unique molecular architecture makes it a valuable building block for synthesizing more complex chemical entities, particularly in pharmaceutical and advanced material research. It is primarily sought by R&D chemists and process development scientists in the fine chemical, agrochemical, and pharmaceutical industries for constructing novel molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), especially those requiring a halogenated aromatic moiety.
• Agrochemical Synthesis: Used in the preparation of advanced herbicides, fungicides, and plant growth regulators where the bromophenyl group imparts specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis, such as cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials, liquid crystals, and polymers where its structure can influence material properties.
• Academic & Industrial R&D: A versatile building block for methodological studies in organic synthesis, including Sonogashira and other palladium-catalyzed couplings.

Basic Information

Product Name	4-(4-Bromophenyl)-2-Methylbut-3-Yn-2-Ol
CAS No.	76347-62-1
Molecular Formula	C11H11BrO
Molecular Weight	239.11 g/mol
Synonyms	2-Methyl-4-(4-bromophenyl)-3-butyn-2-ol; 4-(p-Bromophenyl)-2-methyl-3-butyn-2-ol; 1-(4-Bromophenyl)-3-methyl-1-butyn-3-ol; 3-Butyn-2-ol, 2-methyl-4-(4-bromophenyl)-; p-Bromophenyl methyl butynol
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fine chemical intermediates. Production follows current Good Manufacturing Practices (cGMP) where applicable, and each batch is analyzed to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles (via HPLC/GC) is provided with every shipment to guarantee traceability and support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.