Description

Epirubicinol is a key metabolite and active derivative of the widely used anthracycline chemotherapeutic agent, Epirubicin. This compound is of significant interest in pharmaceutical research and development for its role in understanding drug metabolism, efficacy, and toxicity profiles. It serves as a critical reference standard and intermediate for researchers and manufacturers in the oncology and pharmaceutical sectors, enabling precise analytical work and advanced drug studies. Professionals require this high-purity compound to ensure accurate pharmacokinetic data and support the development of next-generation cancer therapies.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quantitative and qualitative analysis of Epirubicin and its metabolites in biological matrices via HPLC, LC-MS, or other analytical techniques.
• Metabolite Research: Essential for preclinical and clinical studies investigating the metabolic pathway, pharmacokinetics, and pharmacodynamics of Epirubicin.
• Drug Impurity Profiling: Employed in the identification and quantification of process-related impurities and degradation products in Epirubicin active pharmaceutical ingredient (API) and finished drug products.
• Biochemical Assay Development: Serves as a critical reagent in developing and validating cell-based or enzymatic assays to study the mechanism of action and cardiotoxicity of anthracycline drugs.
• Academic & Institutional Research: Utilized in universities and research institutes for fundamental studies on cancer biology, drug resistance mechanisms, and the design of novel anthracycline analogs.

Basic Information

Product Name	Epirubicinol
CAS No.	76155-56-1
Molecular Formula	C27H29NO11
Molecular Weight	543.52 g/mol
Synonyms	13-Dihydroepirubicin; 13-Dihydro-4'-epi-doxorubicin; 4'-Epidoxorubicinol; (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-L-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione; Epirubicin metabolite; 4'-Epiadriamycinol
EINECS	Contact for details

Quality Control

Our Epirubicinol is manufactured and handled under strict quality management systems to ensure the highest standards of purity and consistency, suitable for research and analytical applications. Each batch undergoes comprehensive analysis using advanced techniques such as HPLC, NMR, and mass spectrometry to confirm identity, potency, and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We are committed to meeting the stringent requirements of pharmaceutical R&D and can support compliance with relevant pharmacopeial guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or COA. For long-term storage, consider keeping the product at -20°C under an inert atmosphere to maximize stability. The container should be kept in a dry, well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	Red-orange to red powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.