Description

Cinnamoyl-Coenzyme A is a crucial biochemical intermediate, specifically an activated thioester derivative of cinnamic acid. This compound is essential for research and development in metabolic pathway analysis and enzyme characterization. It serves as a key substrate for studying enzymes like chalcone synthase and other transferases involved in flavonoid and phenylpropanoid biosynthesis. Primary users include biochemical researchers, pharmaceutical developers, and academic institutions focused on plant metabolism, natural product synthesis, and drug discovery.

Application

• Enzyme Substrate for Research: Critical substrate for in vitro assays of acyltransferases, particularly chalcone synthase (CHS), in flavonoid biosynthesis studies.
• Metabolic Pathway Analysis: Used to trace and elucidate the phenylpropanoid pathway in plant and microbial systems.
• Biocatalyst Development: Employed in screening and engineering enzymes for the production of high-value cinnamoyl-derived compounds.
• Pharmaceutical Intermediates: Serves as a building block in the research and development of novel therapeutic agents.
• Biochemical Standard: Used as a reference standard in analytical methods like HPLC and LC-MS for quantifying metabolic flux.
• Natural Product Synthesis: Key intermediate for the chemoenzymatic synthesis of flavonoids, stilbenes, and other polyphenols.

Basic Information

Product Name	Cinnamoyl-Coenzyme A
CAS No.	76109-04-1
Molecular Formula	C30H48N7O17P3S
Molecular Weight	903.72 g/mol
Synonyms	Cinnamoyl-CoA; trans-Cinnamoyl-Coenzyme A; Cinnamoyl Coenzyme A; Coenzyme A, S-cinnamate; S-(3-Oxido-3-oxopropyl) Coenzyme A Cinnamic Thioester; 3'-Phosphoadenosine 5'-(3-{(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-[(3-oxo-3-{[2-(trans-cinnamoylsulfanyl)ethyl]amino}propyl)amino]butyl} dihydrogen diphosphate)
EINECS	Contact for details

Quality Control

Our Cinnamoyl-Coenzyme A is produced under stringent conditions to ensure high purity and batch-to-batch consistency for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity assessment and identity confirmation via spectroscopic methods. A Certificate of Analysis (COA) detailing specific results for purity, identity, and other critical parameters is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white powder or lyophilized solid
Identification (HPLC)	Conforms to reference standard
Identification (UV)	Conforms to reference spectrum
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Biological Activity	Functional as substrate for Chalcone Synthase

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.