Description

Fa-Ala-Osu is a specialized N-hydroxysuccinimide (NHS) ester derivative of the amino acid alanine, protected with a formyl (Fmoc) group. This compound is a critical reagent in peptide synthesis and bioconjugation chemistry, enabling the efficient and selective formation of amide bonds under mild conditions. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors for the development of novel peptides, protein conjugates, and other bioactive molecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): As an activated ester for the controlled incorporation of alanine residues into peptide chains, particularly in Fmoc-based strategies.
• Bioconjugation and Labeling: For the site-specific modification of proteins, antibodies, or other biomolecules with alanine-derived probes, tags, or linkers.
• Proteomics Research: Used in the synthesis of peptide standards, enzyme substrates, or inhibitors for mass spectrometry and biochemical assays.
• Drug Discovery & Development: A key building block in the medicinal chemistry workflow for creating peptide-based drug candidates and therapeutic conjugates.
• Material Science Functionalization: For introducing peptide motifs onto surfaces, nanoparticles, or polymers to create bioactive materials.

Basic Information

Product Name	Fa-Ala-Osu
CAS No.	76079-01-1
Molecular Formula	C19H18N2O6
Molecular Weight	370.36 g/mol
Synonyms	Fmoc-Ala-OSu; N-(9-Fluorenylmethoxycarbonyl)-L-alanine N-hydroxysuccinimide ester; Fmoc-L-alanine N-succinimidyl ester; Fmoc-Alanine-OSu; N-α-Fmoc-L-alanine succinimidyl ester; N-(9-Fluorenylmethyloxycarbonyl)alanine N-hydroxysuccinimide ester; Fmoc-Ala-ONSu; Fmoc-Alanine NHS Ester
EINECS	Contact for details

Quality Control

Our Fa-Ala-Osu is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via IR and NMR spectroscopy. Certificates of Analysis (COA) with detailed specifications are provided to ensure the material meets the stringent requirements for research and cGMP-grade manufacturing applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive) and should be allowed to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMF, DMSO, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.