Description

Desferriferrithiocin is a potent and specific iron chelator belonging to the hydroxypyridinone class of compounds. This high-purity chemical is critical for research and development in fields requiring precise control of iron bioavailability. It serves as a valuable tool compound for scientists and manufacturers in the pharmaceutical and biotechnology sectors. Its primary utility lies in studying iron metabolism and developing novel therapeutic agents.

Application

• Pharmaceutical Research & Development: As a reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel iron chelation therapies.
• Biochemical Research: Used in in vitro and in vivo studies to investigate cellular iron transport, homeostasis, and related metabolic pathways.
• Mechanistic Studies: A key tool for probing the role of iron in oxidative stress, neurodegeneration, and other disease models.
• Analytical Chemistry: Employed as a high-purity standard for method development and validation in chromatographic analysis (HPLC, LC-MS).
• Preclinical Development: Utilized in pharmacokinetic, pharmacodynamic, and toxicology studies for candidate drug molecules targeting iron overload.

Basic Information

Product Name	Desferriferrithiocin
CAS No.	76045-30-2
Molecular Formula	C17H21NO6S
Molecular Weight	367.42 g/mol
Synonyms	Desferrithiocin; DFT; 4,5-Dihydro-2-(3-hydroxy-2-pyridinyl)-4-methyl-4-thiazolecarboxylic Acid; L-4,5-Dihydro-2-(3-hydroxy-2-pyridinyl)-4-methyl-4-thiazolecarboxylic Acid; (S)-4,5-Dihydro-2-(3-hydroxy-2-pyridin-2-yl)-4-methyl-4-thiazolecarboxylic Acid; CP20; NSC 696174; DFX Analog
EINECS	Contact for details

Quality Control

Our Desferriferriothiocin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification (IR, NMR), purity assay (HPLC), and control of related substances and residual solvents, to ensure it meets stringent research-grade specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.