Description

Sterigmatocystin1,2-Oxide is a chemically modified derivative of the mycotoxin sterigmatocystin, characterized by the presence of an epoxide functional group. This compound is of significant interest in research and analytical chemistry as a key reference standard and metabolite for studying the toxicology and metabolic pathways of sterigmatocystin and related aflatoxins. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, food safety, and agricultural sectors for method development, calibration, and toxicological studies.

Application

• Analytical Reference Standard: Primary use as a certified standard for the accurate quantification and identification of sterigmatocystin and its metabolites in complex matrices via HPLC, LC-MS, or GC-MS.
• Toxicology Research: Critical for in-vitro and in-vivo studies investigating the mutagenic, carcinogenic, and cytotoxic mechanisms of epoxide-containing mycotoxins.
• Metabolic Pathway Studies: Used to elucidate the biotransformation and detoxification pathways of sterigmatocystin in biological systems.
• Food & Feed Safety Testing: Employed in the development and validation of analytical methods to monitor mycotoxin contamination in grains, nuts, and animal feed.
• Pharmaceutical Impurity Profiling: Serves as a potential impurity marker or degradation product in relevant pharmaceutical research.
• Biochemical Reagent: Used in enzymatic studies to understand the activity of epoxide hydrolases and other detoxifying enzymes.

Basic Information

Product Name	Sterigmatocystin1,2-Oxide
CAS No.	76014-27-2
Molecular Formula	C18H12O7
Molecular Weight	340.28 g/mol
Synonyms	Sterigmatocystin 1,2-epoxide; 1,2-Epoxysterigmatocystin; Sterigmatocystin epoxide; 3a,12c-Dihydro-8-hydroxy-6-methoxy-7H-furo[3',2':4,5]furo[2,3-h][1]benzopyran-7-one, 1,2-epoxide derivative; Sterigmatocystin-1,2-oxide
EINECS	Contact for details

Quality Control

Our Sterigmatocystin1,2-Oxide is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity confirmation and structural verification by spectroscopic methods (NMR, MS). A detailed Certificate of Analysis (COA) is provided, ensuring traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	Off-white to pale yellow solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, acetone; sparingly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.