Description

2,2,2-Trifluoro-n-(4-Isopropylphenyl)Acetamide is a specialized fluorinated acetamide derivative, serving as a high-value synthetic intermediate in advanced chemical manufacturing. Its core value lies in the unique trifluoromethyl group, which imparts desirable properties like enhanced metabolic stability and lipophilicity to target molecules. This compound is critically needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the fluorine atoms enhance biological activity and environmental persistence.
• Material Science Research: Serves as a precursor for fluorinated polymers and liquid crystals, contributing to materials with unique thermal and chemical resistance.
• Organic Synthesis Reagent: Employed in cross-coupling reactions and amide bond formation to introduce the 4-isopropylphenyl moiety into complex molecular architectures.
• Biochemical Probe Development: Utilized in medicinal chemistry to create molecular probes for studying enzyme interactions and receptor binding sites.

Basic Information

Product Name	2,2,2-Trifluoro-n-(4-Isopropylphenyl)Acetamide
CAS No.	75999-61-0
Molecular Formula	C11H12F3NO
Molecular Weight	231.21 g/mol
Synonyms	N-(4-Isopropylphenyl)-2,2,2-trifluoroacetamide; 2,2,2-Trifluoro-N-[4-(1-methylethyl)phenyl]acetamide; 4-Isopropyl-2,2,2-trifluoroacetanilide; α,α,α-Trifluoro-N-(p-isopropylphenyl)acetamide; TFIPA; Trifluoroacet-4-isopropylanilide; p-Isopropyl-α,α,α-trifluoroacetanilide
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-n-(4-Isopropylphenyl)Acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.