Description

Leukotriene A Methyl Ester CAS NO 75879-18-4 is a key synthetic intermediate in the production of leukotriene analogs and related bioactive lipid mediators. This compound is of significant value for pharmaceutical research and development, particularly in the study of inflammatory pathways and respiratory diseases. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in drug discovery and advanced biochemical synthesis.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of leukotriene receptor antagonists and other anti-inflammatory drug candidates.
• Biochemical Research: Used as a reference standard and precursor in studies investigating arachidonic acid metabolism and eicosanoid signaling pathways.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to develop new therapeutic agents targeting asthma and allergies.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses to produce high-value, complex molecules for biological evaluation.
• Academic Research: Utilized in university and institutional labs for fundamental research in immunology and pharmacology.

Basic Information

Product Name	Leukotriene A Methyl Ester
CAS No.	75879-18-4
Molecular Formula	C21H32O4
Molecular Weight	348.48 g/mol
Synonyms	LTA4 Methyl Ester; Methyl (5S,6S)-5,6-Epoxy-7,9,11,14-eicosatetraenoate; Methyl 5,6-oxido-7,9,11,14-eicosatetraenoate; Leukotriene A4 Methyl Ester; 5,6-Oxido-7,9,11,14-eicosatetraenoic Acid Methyl Ester; (5S,6S)-5,6-Epoxy-7,9,11,14-eicosatetraenoic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our Leukotriene A Methyl Ester is produced under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality commitment aligns with the standards expected in fine chemical and pharmaceutical intermediate supply.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and degradation. For long-term storage, keep the material in a freezer. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solubility	Soluble in ethanol, methanol, DMSO, and common organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.