Description

5,5'-[(1,3-Dioxo-1,3-Propanediyl)Bis(Methylimino)]Bis[N,N'-Bis[2-Hydroxy-1-(Hydroxymethyl)Ethyl]-2,4,6-Triiodo-1,3-Benzenedicarboxamide] is a high-purity, non-ionic iodinated contrast agent intermediate. This compound matters for its critical role in the synthesis of advanced, low-osmolality X-ray contrast media, which are essential for enhanced medical imaging diagnostics. Pharmaceutical manufacturers and advanced chemical synthesis facilities require this high-value intermediate to produce safer and more effective contrast agents for procedures like angiography, urography, and computed tomography (CT) scans.

Application

• Primary Intermediate for Iodinated Contrast Media: Key building block in the synthesis of modern, non-ionic X-ray contrast agents such as Iopamidol, Iohexol, and Ioversol.
• Pharmaceutical Active Pharmaceutical Ingredient (API) Synthesis: Used in controlled chemical processes to manufacture the final active ingredient for injectable diagnostic solutions.
• Research & Development: Serves as a crucial reference standard and starting material in the R&D of next-generation contrast agents with improved safety profiles.
• Specialty Chemical Manufacturing: Employed in fine chemical production for creating customized diagnostic molecules with specific pharmacokinetic properties.

Basic Information

Item	Details
Product Name	5,5'-[(1,3-Dioxo-1,3-Propanediyl)Bis(Methylimino)]Bis[N,N'-Bis[2-Hydroxy-1-(Hydroxymethyl)Ethyl]-2,4,6-Triiodo-1,3-Benzenedicarboxamide]
CAS No.	75871-98-6
Molecular Formula	C37H44I6N6O16
Molecular Weight	1626.19 g/mol
Synonyms	Iopamidol Impurity; Iopamidol Related Compound; 5,5'-[1,3-Dioxo-1,3-propanediyl)bis(methylimino)]bis[N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide]; Bis(des-hydroxyacetyl) Iopamidol; Iopamidol Dimer Precursor; N,N'-Bis[2,3-Dihydroxypropyl]-2,4,6-triiodo-5-[(methylamino)carbonyl]isophthalamide Dimer; Iohexol Related Compound A (Structural Isomer); Non-ionic Contrast Agent Intermediate
EINECS	Contact for details

Quality Control

Our 5,5'-[(1,3-Dioxo-1,3-Propanediyl)Bis(Methylimino)]Bis[N,N'-Bis[2-Hydroxy-1-(Hydroxymethyl)Ethyl]-2,4,6-Triiodo-1,3-Benzenedicarboxamide] is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate use. Certificates of Analysis (COA) with full traceability are provided and can be tailored to meet specific pharmacopeial standards (e.g., USP, EP) upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤ 10 ppm
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.