Description

Zomepirac Glucuronide is a significant metabolite of the non-steroidal anti-inflammatory drug (NSAID) zomepirac. This compound is primarily utilized as a critical reference standard in pharmaceutical research and development, particularly in the fields of drug metabolism and pharmacokinetics (DMPK). It is essential for scientists and quality control laboratories involved in bioanalytical method development, metabolite identification, and ensuring the safety and efficacy of pharmaceutical products.

Application

• Pharmaceutical Reference Standard: Serves as a certified standard for the quantitative and qualitative analysis of zomepirac metabolites in biological matrices.
• Drug Metabolism Studies: Used to investigate the metabolic pathways, clearance mechanisms, and pharmacokinetic profile of zomepirac.
• Bioanalytical Method Development: Critical for developing and validating sensitive HPLC, LC-MS, or LC-MS/MS methods for metabolite detection.
• Toxicology and Safety Assessment: Employed in studies to understand the safety profile and potential toxicological implications of drug metabolites.
• Clinical Research: Supports studies monitoring metabolite levels in patients during clinical trials or therapeutic drug monitoring.
• Impurity Profiling: Acts as a known impurity or degradation product reference in the quality control of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Zomepirac Glucuronide
CAS No.	75871-31-7
Molecular Formula	C24H24N2O10
Molecular Weight	500.46 g/mol
Synonyms	Zomepirac 1-O-β-Acetylglucuronide; Zomepirac Acyl Glucuronide; 1-β-O-{5-(4-Chlorobenzoyl)-1,4-dimethyl-1H-pyrrol-2-yl}acetyl glucopyranuronic acid; Zomepirac O-Glucuronide; ZOMAX Glucuronide Metabolite; Zomepirac Glucuronide Metabolite; CL 71563 Glucuronide
EINECS	Contact for details

Quality Control

Our Zomepirac Glucuronide is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and reference materials. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.