Description

4-((Trimethylsilyl)Ethynyl)Aniline is a specialized organosilicon building block featuring a reactive aniline group and a protected ethynyl functionality. This compound is valued for its role as a key intermediate in advanced organic synthesis, particularly in the construction of complex molecular architectures. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A crucial synthon for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where its structural motifs can contribute to biological activity.
• Material Science & Polymer Chemistry: Serves as a monomer or cross-linking agent in the production of specialty polymers, dendrimers, and silicon-containing advanced materials.
• Organic Electronics: Employed in the synthesis of conjugated molecules and molecular wires for applications in OLEDs, OFETs, and other electronic devices.
• Chemical Research & Development: A versatile reagent for Sonogashira coupling and other palladium-catalyzed cross-coupling reactions to create complex alkynes.
• Ligand & Catalyst Preparation: Used to synthesize novel ligands for catalysis or as a precursor for metal-organic frameworks (MOFs).

Basic Information

Product Name	4-((Trimethylsilyl)Ethynyl)Aniline
CAS No.	75867-39-9
Molecular Formula	C11H17NSi
Molecular Weight	191.35 g/mol
Synonyms	4-(Trimethylsilylethynyl)aniline; 4-(2-Trimethylsilylethynyl)aniline; 4-Ethynyl-N-(trimethylsilyl)aniline; 4-Aminophenyl(trimethylsilyl)acetylene; p-((Trimethylsilyl)ethynyl)aniline; Benzenamine, 4-[(trimethylsilyl)ethynyl]-; 4-TMS-ethynylaniline
EINECS	Contact for details

Quality Control

Our 4-((Trimethylsilyl)Ethynyl)Aniline is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, GC, NMR, and FTIR to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. This material is hygroscopic and easily oxidized; ensure containers are sealed immediately after use to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.