Description

Rimcazole CAS NO 75859-04-0 is a selective sigma receptor antagonist with significant research interest in the field of neuropharmacology. Its primary value lies in its utility as a critical reference standard and a key chemical tool for investigating central nervous system (CNS) disorders and receptor mechanisms. This compound is essential for pharmaceutical R&D laboratories, academic research institutions, and analytical facilities focused on neuroscience, psychopharmacology, and drug discovery.

Application

• Neuroscience Research: Used as a selective σ-1 receptor antagonist to study receptor function, signal transduction, and behavioral effects in preclinical models.
• Psychopharmacology Studies: A vital tool for investigating the role of sigma receptors in conditions such as schizophrenia, depression, anxiety, and substance abuse.
• Drug Discovery & Development: Serves as a reference compound and a starting point for the design and synthesis of novel therapeutic agents targeting CNS pathways.
• Biochemical Assays: Employed in in vitro binding assays and functional studies to characterize drug-receptor interactions and screen for new ligands.
• Analytical Reference Standard: Provides a high-purity benchmark for method development, validation, and quality control in analytical chemistry (e.g., HPLC, LC-MS).
• Academic & Clinical Research: Supports fundamental research into neurochemical mechanisms and the potential therapeutic modulation of sigma receptors.

Basic Information

Product Name	Rimcazole
CAS No.	75859-04-0
Molecular Formula	C21H27N3O
Molecular Weight	337.46 g/mol
Synonyms	Rimcazole Hydrochloride; BW 234U; cis-9-[3-(3,5-Dimethyl-1-piperazinyl)propyl]carbazole; (9R,10S)-9-[3-(3,5-Dimethylpiperazin-1-yl)propyl]-9,10-dihydrocarbazole; (9R,10S)-9-[3-(3,5-Dimethyl-1-piperazinyl)propyl]-9,10-dihydro-4bH-carbazole
EINECS	Contact for details

Quality Control

Our Rimcazole is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee compliance with your research-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.