Description

Ethanone, 2,2,2-Trifluoro-1-(4-Methoxy-3-Methylphenyl)- (9Ci) is a specialized trifluoromethyl ketone derivative, a key structural motif valued for its unique electronic and steric properties. This compound is significant as a versatile building block and intermediate in advanced organic synthesis, particularly where the introduction of a trifluoroacetyl group is required. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and stability.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials and specialty polymers with tailored properties.
• Fluorine Chemistry Studies: A valuable compound for academic and industrial research focused on understanding and applying fluorine-containing functional groups.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this precise chemical entity.

Basic Information

Product Name	Ethanone, 2,2,2-Trifluoro-1-(4-Methoxy-3-Methylphenyl)- (9Ci)
CAS No.	75822-11-6
Molecular Formula	C10H9F3O2
Molecular Weight	218.17 g/mol
Synonyms	1-(4-Methoxy-3-methylphenyl)-2,2,2-trifluoroethanone; 2,2,2-Trifluoro-1-(4-methoxy-3-methylphenyl)ethanone; 4-Methoxy-3-methyl-α,α,α-trifluoroacetophenone; 3-Methyl-4-methoxy-α,α,α-trifluoroacetophenone; α,α,α-Trifluoro-4'-methoxy-3'-methylacetophenone; TFMMAP (abbreviation); Trifluoroacetyl derivative of 4-methoxy-3-methylbenzene
EINECS	Contact for details

Quality Control

Our Ethanone, 2,2,2-Trifluoro-1-(4-Methoxy-3-Methylphenyl)- (9Ci) is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.