Description

1-Chloro-4-(1,1,2,2-Tetrafluoroethoxy)Benzene is a high-value fluorinated aromatic ether building block. This compound is significant for its role in advanced material science and pharmaceutical development, where its unique fluorine-containing side chain imparts desirable properties like enhanced stability and lipophilicity. It is primarily needed by R&D chemists and process engineers in the agrochemical, pharmaceutical, and specialty polymer industries for synthesizing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs for metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the fluorinated ethoxy group can enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated components for electronic display technologies and organic light-emitting diodes (OLEDs).
• Specialty Polymer Modifier: Incorporated into polymer chains to alter surface properties, chemical resistance, and thermal stability of high-performance plastics and coatings.
• Chemical Research & Development: A versatile building block in medicinal chemistry and material science research for exploring structure-activity relationships (SAR).

Basic Information

Product Name	1-Chloro-4-(1,1,2,2-Tetrafluoroethoxy)Benzene
CAS No.	75820-58-5
Molecular Formula	C8H5ClF4O
Molecular Weight	228.57 g/mol
Synonyms	p-Chloro(1,1,2,2-tetrafluoroethoxy)benzene; 4-Chloro-1-(1,1,2,2-tetrafluoroethoxy)benzene; 1-Chloro-4-(1,1,2,2-tetrafluoroethoxy)benzene; 4-(1,1,2,2-Tetrafluoroethoxy)chlorobenzene; Benzene, 1-chloro-4-(1,1,2,2-tetrafluoroethoxy)-; Tetrafluoroethoxy chlorobenzene
EINECS	Contact for details

Quality Control

Our 1-Chloro-4-(1,1,2,2-Tetrafluoroethoxy)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and fluorides. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.