Description

N,n-Dimethyl Z-Dl-Alaninamide CAS NO 75801-52-4 is a protected amino acid derivative, specifically an N,N-dimethyl amide of Z-protected DL-alanine. This compound serves as a crucial chiral building block and intermediate in advanced organic synthesis, offering controlled reactivity for the construction of complex peptide and peptidomimetic structures. It is primarily utilized by research institutions and pharmaceutical development companies engaged in medicinal chemistry, process development, and the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of peptide-based drugs, protease inhibitors, and other therapeutic agents.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and the development of novel pharmacophores.
• Peptide Synthesis: Serves as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis (SPPS).
• Chiral Auxiliary/Resolving Agent: Potential use in asymmetric synthesis due to its chiral center, aiding in the preparation of enantiomerically pure compounds.
• Bioconjugation & Labeling: Intermediate for creating modified peptides or conjugates for diagnostic or targeted delivery applications.
• Academic & Industrial R&D: Fundamental reagent in organic chemistry laboratories for method development and exploring new synthetic pathways.

Basic Information

Product Name	N,n-Dimethyl Z-Dl-Alaninamide
CAS No.	75801-52-4
Molecular Formula	C₁₃H₁₈N₂O₃
Molecular Weight	250.30 g/mol
Synonyms	Z-DL-Ala-NMe2; N,N-Dimethyl-N-[(benzyloxy)carbonyl]-DL-alaninamide; (RS)-N,N-Dimethyl-2-[(benzyloxycarbonyl)amino]propanamide; Benzyl (1RS)-1-(dimethylcarbamoyl)ethylcarbamate; DL-Alanine, N-[(phenylmethoxy)carbonyl]-, N',N'-dimethylamide; Carbamic acid, N-[(1RS)-1-(dimethylamino)carbonyl]ethyl]-, phenylmethyl ester
EINECS	Contact for details

Quality Control

Our N,n-Dimethyl Z-Dl-Alaninamide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and spectroscopic identification (NMR, IR), to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	DL-mixture (Racemic)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.