Description

Piridronic Acid CAS NO 75755-07-6 is a bisphosphonate compound belonging to the pyridine-containing class of drugs. It is a high-purity active pharmaceutical ingredient (API) of significant interest for its role in modulating bone metabolism. This compound is primarily utilized by pharmaceutical manufacturers and research institutions developing treatments for bone-related disorders. Its specific molecular structure makes it a key intermediate for targeted therapeutic applications.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of advanced bisphosphonate drugs for osteoporosis and Paget's disease.
• Bone Resorption Inhibitor Research: Used in preclinical and clinical research to study mechanisms for inhibiting osteoclast activity and bone turnover.
• Radiopharmaceutical Precursor: Potential use as a chelating agent or precursor in developing bone-seeking radiopharmaceuticals for diagnostic imaging or therapy.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Metabolic Bone Disease Studies: Applied in biochemical research to investigate calcium metabolism and pathways involved in skeletal disorders.

Basic Information

Product Name	Piridronic Acid
CAS No.	75755-07-6
Molecular Formula	C5H8NO7P2
Molecular Weight	255.06 g/mol
Synonyms	Piridronic Acid; 3-Amino-1-hydroxypropylidene-1,1-bisphosphonic acid; APD; 3-APB; 3-Amino-1-hydroxypropylidene-1,1-diphosphonic acid; (3-Amino-1-hydroxypropylidene)bisphosphonic acid; Amino-hydroxy-propylidene-bisphosphonic acid; Piridronate
EINECS	Contact for details

Quality Control

Our Piridronic Acid is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) is provided, detailing parameters such as assay, purity by HPLC, identification, and impurity profiles. We adhere to cGMP principles where applicable to ensure product consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.