Description

Pentosan Polysulfate Sodium is a semi-synthetic, sulfated polysaccharide derivative derived from xylan, primarily sourced from beechwood. Its unique chemical structure confers significant biological activity, making it a valuable compound for advanced therapeutic and research applications. This product is essential for pharmaceutical manufacturers, biotechnology researchers, and developers of medical devices seeking high-purity, bioactive agents.

Application

• Pharmaceutical Intermediates: Key starting material for the synthesis of anticoagulant and antithrombotic drugs.
• Osteoarthritis Treatment: Used in clinical research and formulations for viscosupplementation and symptom management.
• Interstitial Cystitis Therapy: An active pharmaceutical ingredient (API) in approved medications for bladder pain syndrome.
• Veterinary Medicine: Employed in equine and canine joint health supplements and treatments.
• Biomedical Research: Utilized in studies of glycosaminoglycan (GAG) analogs, inflammation modulation, and cartilage biology.
• Medical Device Coatings: Applied to enhance the hemocompatibility of stents, catheters, and other blood-contacting devices.

Basic Information

Product Name	Pentosan Polysulfate Sodium
CAS No.	37319-17-8
Molecular Formula	(C5H7Na2O11S2)n
Molecular Weight	~4000-6000 Da (Average)
Synonyms	PPS; PPS Sodium; Sodium Pentosan Polysulfate; SP-54; Xylan Polysulfate Sodium Salt; Elmiron (Brand Name); 4-Methylumbelliferyl-β-D-xylopyranoside derivative; (1→4)-β-Xylan, hydrogen sulfate, sodium salt
EINECS	Contact for details

Quality Control

Our Pentosan Polysulfate Sodium is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) is provided, detailing parameters such as assay, sulfate content, molecular weight distribution, and impurity profiles. We support compliance with cGMP and relevant pharmacopeial guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent absorption of water.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Sulfate Content	15.0 - 20.0 %
pH (1% Solution)	5.5 - 7.5
Loss on Drying	≤ 5.0 %
Residue on Ignition	20.0 - 28.0 %
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.