Description

Ibandronic Acid CAS NO 114084-78-5 is a potent bisphosphonate compound that serves as a critical active pharmaceutical ingredient (API). It is primarily valued for its ability to inhibit osteoclast-mediated bone resorption, making it essential for managing bone-related disorders. This high-purity chemical is indispensable for pharmaceutical manufacturers and research institutions developing treatments for osteoporosis, hypercalcemia of malignancy, and metastatic bone disease.

Application

• Pharmaceutical API: Primary use as the active ingredient in the synthesis of Ibandronate Sodium, a medication for osteoporosis and bone metastasis.
• Osteoporosis Treatment: Key component in formulations designed to increase bone mineral density and reduce fracture risk in postmenopausal women.
• Oncological Support: Used in therapies to prevent skeletal-related events (SREs) such as fractures and spinal cord compression in patients with bone metastases.
• Hypercalcemia Management: Employed in pharmaceutical preparations to lower elevated calcium levels in the blood caused by cancer.
• Biomedical Research: Serves as a reference standard and key intermediate in pharmacological studies of bone metabolism and bisphosphonate action mechanisms.
• Veterinary Medicine: Investigated for potential applications in treating bone disorders in animals.

Basic Information

Product Name	Ibandronic Acid
CAS No.	114084-78-5
Molecular Formula	C9H23NO7P2
Molecular Weight	319.23 g/mol
Synonyms	Ibandronate; Ibandronic Acid Monohydrate; 1-Hydroxy-3-(methylpentylamino)propylidene-1,1-bisphosphonic Acid; Bonviva Acid; Bondronat Acid; (1-Hydroxy-3-(N-methyl-N-pentylamino)propane-1,1-diyl)bis(phosphonic acid); BM 21.0955; CGP 42'446
EINECS	Contact for details

Quality Control

Our Ibandronic Acid is manufactured under strict quality systems. Each batch is tested to meet high-purity standards suitable for pharmaceutical applications, with specifications aligning with major pharmacopoeial guidelines. A comprehensive Certificate of Analysis (COA) is provided for every shipment, detailing identity, purity, and impurity profiles to ensure supply reliability and regulatory compliance for our global B2B partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	≥ 98.5%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.