Description

Risedronic Acid CAS NO 105462-24-6 is a high-purity bisphosphonate compound, a key intermediate in the synthesis of risedronate sodium, a widely prescribed medication for osteoporosis and Paget's disease. Its consistent quality and precise chemical structure are critical for ensuring the efficacy and safety of the final active pharmaceutical ingredient (API). This material is essential for pharmaceutical manufacturers, research institutions, and fine chemical suppliers engaged in the development and production of bone metabolism therapeutics.

Application

• Primary Pharmaceutical Intermediate: The principal use is in the synthesis of Risedronate Sodium, the active ingredient in anti-resorptive medications.
• API Development: Serves as a critical building block in research and development for new bisphosphonate-based drug formulations.
• Reference Standard: Used as a high-purity chemical reference standard (CRS) for quality control and analytical method validation in pharmaceutical labs.
• Biochemical Research: Employed in preclinical studies to investigate the mechanism of action of bisphosphonates on bone metabolism and related pathways.
• Fine Chemical Synthesis: Acts as a specialized intermediate for synthesizing novel compounds with potential therapeutic applications in bone disorders.

Basic Information

Product Name	Risedronic Acid
CAS No.	105462-24-6
Molecular Formula	C7H11NO7P2
Molecular Weight	283.11 g/mol
Synonyms	Risedronic Acid; 1-Hydroxy-2-(3-pyridinyl)ethylidene-1,1-bisphosphonic Acid; 2-(3-Pyridinyl)-1-hydroxyethylidene-1,1-bisphosphonic Acid; NE-10245; Risedronate Acid Form; [1-Hydroxy-1-phosphono-2-(3-pyridinyl)ethyl]phosphonic Acid; Risedronic Acid (Free Acid)
EINECS	Contact for details

Quality Control

Our Risedronic Acid is manufactured under strict quality management systems to meet the exacting standards of the pharmaceutical industry. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, identification by IR and NMR spectroscopy, and tests for residual solvents and related substances. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.