Description

Cefmenoxime Hydrochloride is a semi-synthetic, broad-spectrum cephalosporin antibiotic. It is valued for its potent activity against a wide range of Gram-positive and Gram-negative bacteria, including β-lactamase-producing strains. This compound is primarily utilized in pharmaceutical research, development, and manufacturing for the formulation of injectable antibiotic products.

Application

• Pharmaceutical Active Ingredient (API): Core component in the manufacture of injectable antibiotic formulations.
• Clinical Research: Used in studies investigating treatments for serious bacterial infections such as sepsis, pneumonia, and complicated urinary tract infections.
• Reference Standard: Serves as a high-purity analytical standard for quality control testing in pharmaceutical laboratories.
• Antimicrobial Susceptibility Testing: Employed in microbiological assays to determine bacterial resistance profiles.
• Drug Development Intermediates: Used in the synthesis of novel cephalosporin derivatives and prodrugs.

Basic Information

Product Name	Cefmenoxime Hydrochloride
CAS No.	75738-58-8
Molecular Formula	C16H17N9O5S3 • HCl
Molecular Weight	580.02 g/mol
Synonyms	Cefmenoxime HCl; (6R,7R)-7-[(Z)-2-(2-Amino-4-thiazolyl)-2-methoxyiminoacetamido]-3-[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrochloride; SCE-1365; CMX; Cefmenoxime Hemihydrochloride
EINECS	Contact for details

Quality Control

Our Cefmenoxime Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identification by IR and NMR spectroscopy, and tests for related substances and residual solvents. We provide Certificates of Analysis (COA) that detail compliance with in-house specifications aligned with pharmaceutical industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
pH (1% solution)	3.0 - 5.0
Specific Optical Rotation	+55° to +65° (c=1, in H2O)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.