Description

2-Acetyl-3-Ethoxy-n-(4-Trifluoromethylphenyl)Acrylamide is a specialized fine chemical intermediate featuring a unique trifluoromethylphenyl-acrylamide core structure. This compound is valued for its role in advanced organic synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing complex molecules with potential bioactive properties.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, especially those targeting specific enzyme inhibitors or receptor modulators.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, or insecticides, where the trifluoromethyl group can enhance biological activity and stability.
• Organic Synthesis Reagent: Serves as a versatile acrylamide derivative for Michael additions, cyclization reactions, and the construction of heterocyclic compounds in academic and industrial laboratories.
• Material Science Precursor: Potential use in the synthesis of specialty polymers or functional materials that require fluorinated aromatic components for specific thermal or chemical resistance properties.
• Chemical Biology Probe Development: Utilized in creating molecular probes for studying biological pathways and protein interactions due to its ability to act as an electrophilic trap or labeling agent.

Basic Information

Product Name	2-Acetyl-3-Ethoxy-n-(4-Trifluoromethylphenyl)Acrylamide
CAS No.	75706-11-5
Molecular Formula	C₁₆H₁₆F₃NO₃
Molecular Weight	327.30 g/mol
Synonyms	2-Acetyl-3-ethoxy-N-[4-(trifluoromethyl)phenyl]acrylamide; 2-Acetyl-3-ethoxy-N-(4-trifluoromethylphenyl)acrylamide; N-(4-Trifluoromethylphenyl)-2-acetyl-3-ethoxyacrylamide; 2-Acetyl-3-ethoxy-N-(α,α,α-trifluoro-p-tolyl)acrylamide; Acrylamide, 2-acetyl-3-ethoxy-N-[4-(trifluoromethyl)phenyl]-; (2E)-2-Acetyl-3-ethoxy-N-[4-(trifluoromethyl)phenyl]prop-2-enamide
EINECS	Contact for details

Quality Control

Every batch of 2-Acetyl-3-Ethoxy-n-(4-Trifluoromethylphenyl)Acrylamide is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocols are designed to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in a dark place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.