Description

2,2,2-Trifluoro-1-p-Tolyl-Ethanoneoxime is a specialized fluorinated oxime compound, serving as a critical building block in advanced organic synthesis. Its unique trifluoromethyl and oxime functional groups make it a valuable intermediate for constructing complex molecules with enhanced properties. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to introduce fluorine atoms and oxime functionalities into target structures to modulate bioactivity, metabolic stability, and physical characteristics.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can improve lipophilicity and biological activity.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, or organic electronic materials requiring fluorinated aromatic components.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological mechanisms and enzyme inhibition.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions to create complex biaryl structures.
• Ligand and Catalyst Development: Potential building block for creating novel chiral ligands or organocatalysts used in asymmetric synthesis.

Basic Information

Item	Detail
Product Name	2,2,2-Trifluoro-1-p-Tolyl-Ethanoneoxime
CAS No.	75703-25-2
Molecular Formula	C9H8F3NO
Molecular Weight	203.16 g/mol
Synonyms	2,2,2-Trifluoro-1-(4-methylphenyl)ethanone oxime; α,α,α-Trifluoro-4-methylacetophenone oxime; 1-(4-Methylphenyl)-2,2,2-trifluoroethanone oxime; p-Methyl-α,α,α-trifluoroacetophenone oxime; 4-Methyl-α,α,α-trifluoroacetophenone oxime; Trifluoro-p-tolyl ketoxime; (4-Methylphenyl)(trifluoromethyl)methanone oxime
EINECS	Contact for details

Quality Control

Every batch of 2,2,2-Trifluoro-1-p-Tolyl-Ethanoneoxime is produced and tested under a strict quality management system. We ensure high purity and consistency through advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.