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Glycodeoxycholic Acid-3-o-β-Glucuronide Disodium Salt CAS NO 75672-36-5


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CAS No.:75672-36-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Glycodeoxycholic Acid-3-o-β-Glucuronide Disodium Salt is a high-purity, conjugated bile acid derivative, specifically the disodium salt of the 3-O-β-glucuronide of glycodeoxycholic acid. This compound is of significant value as a critical reference standard and biochemical reagent for metabolic and pharmacokinetic studies. It is primarily required by pharmaceutical R&D laboratories, diagnostic manufacturers, and academic research institutions focusing on liver function, bile acid metabolism, and drug interaction pathways.

Application

  • Pharmaceutical Reference Standard: For the quantitative analysis and quality control of bile acid metabolites in drug development and formulation.
  • Biochemical Research: As a substrate or inhibitor in enzymatic studies related to glucuronidation and bile acid transporters.
  • Diagnostic Kit Development: Used in the calibration and validation of clinical diagnostic assays for liver and gastrointestinal disorders.
  • Metabolite Identification: Serves as a confirmed metabolite standard in ADME (Absorption, Distribution, Metabolism, and Excretion) studies for new chemical entities.
  • Academic Research: Investigating the role of specific bile acid conjugates in cellular signaling, inflammation, and disease pathology.

Basic Information

Product Name Glycodeoxycholic Acid-3-o-β-Glucuronide Disodium Salt
CAS No. 75672-36-5
Molecular Formula C32H51NNa2O11
Molecular Weight 671.73 g/mol
Synonyms Glycodeoxycholic Acid 3-O-β-D-Glucuronide Disodium Salt; 3-O-(β-D-Glucopyranosyluronic acid)glycodeoxycholic Acid Disodium Salt; GDCA-3G Na2; N-[(3α,5β,12α)-3,12-Dihydroxy-24-oxocholan-24-yl]glycine 3-O-β-D-Glucopyranosiduronic Acid Disodium Salt; Chemodeoxycholylglycine 3-O-β-Glucuronide Disodium Salt; Disodium (4R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoylamino]acetate 3-O-β-D-glucopyranosiduronate
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Quality Control

Our Glycodeoxycholic Acid-3-o-β-Glucuronide Disodium Salt is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and MS, to ensure it meets the exacting standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccant in the container.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 5.0%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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