Description

β-D-Glucopyranosiduronic Acid, (3α,5β,7β)-23-Carboxy-7-Hydroxy-24-Norcholan-3-Yl, Disodium Salt (9Ci) is a high-purity, chemically defined bile acid derivative. This compound is of significant value in pharmaceutical research and development, particularly as a key intermediate or reference standard for studying metabolic pathways and liver function. It is primarily required by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in hepatology, gastroenterology, and steroid chemistry.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel therapeutic agents targeting liver and metabolic disorders.
• Biochemical Research: Used as a reference standard or substrate in enzymatic assays and metabolic studies related to bile acid conjugation and transport.
• Analytical Standard: Employed in high-performance liquid chromatography (HPLC) and mass spectrometry (MS) for the qualitative and quantitative analysis of complex biological samples.
• Metabolite Studies: Facilitates research into drug metabolism and pharmacokinetics (DMPK), especially for compounds processed through hepatic pathways.
• Diagnostic Development: Potential use in the development of diagnostic kits or assays for liver function and cholestatic diseases.

Basic Information

Product Name	β-D-Glucopyranosiduronic Acid, (3α,5β,7β)-23-Carboxy-7-Hydroxy-24-Norcholan-3-Yl, Disodium Salt (9Ci)
CAS No.	75672-30-9
Molecular Formula	C31H46Na2O11
Molecular Weight	640.68 g/mol
Synonyms	Disodium Tauro-7β-hydroxy-3-oxochol-24-oate glucuronide; 7β-Hydroxy-3-oxochol-24-oic acid glucuronide disodium salt; Tauro-7β-hydroxy-3-oxocholan-24-oic acid β-D-glucuronide disodium salt; Norcholan-3-yl glucuronide derivative; Bile acid glucuronide disodium salt; (3α,5β,7β)-23-Carboxy-7-hydroxy-24-norcholan-3-yl β-D-glucopyranosiduronic acid disodium salt
EINECS	Contact for details

Quality Control

Our β-D-Glucopyranosiduronic Acid derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We can support development projects requiring compliance with cGMP or other relevant guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation due to moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	Contact for details
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.