Description

Enkephalin, Alanyl(2)-n-(2-(Dimethylamino)Ethyl)-N(Alpha)-Methyl-Phenylalaninamide(4)- CAS NO 75638-63-0 is a synthetic peptide analog of the endogenous enkephalin neuropeptides, designed for enhanced stability and receptor binding affinity. This compound is critical for advanced research in neuropharmacology and pain management, serving as a potent and selective ligand for opioid receptor studies. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on developing novel central nervous system (CNS) therapeutics and diagnostic tools.

Application

• Neuroscience Research: As a key tool compound for investigating the structure, function, and signaling pathways of delta and mu opioid receptors.
• Drug Discovery & Development: Serving as a reference standard or a lead compound in the design of new analgesic and neuroprotective agents with reduced side-effect profiles.
• Biochemical Assays: Used in competitive binding assays, receptor autoradiography, and functional cellular assays to screen and characterize new chemical entities.
• Academic Studies: Fundamental research on pain mechanisms, addiction, mood disorders, and the role of the endogenous opioid system.
• Peptide Chemistry & Conjugation: Acting as a model substrate for studying peptide stability, modification techniques, and the development of peptide-drug conjugates.

Basic Information

Product Name	Enkephalin, Alanyl(2)-n-(2-(Dimethylamino)Ethyl)-N(Alpha)-Methyl-Phenylalaninamide(4)- CAS NO 75638-63-0
CAS No.	75638-63-0
Molecular Formula	C28H41N7O4
Molecular Weight	539.67 g/mol
Synonyms	H-Tyr-D-Ala-Gly-Phe-NH-CH2CH2N(CH3)2; DADLE analog; [D-Ala2, Leu5]-Enkephalin derivative; Tyr-D-Ala-Gly-Phe-Leu derivative; Opioid receptor peptide ligand; 75638-63-0; Alanyl(2)-n-(2-(Dimethylamino)Ethyl)-N(Alpha)-Methyl-Phenylalaninamide(4)-Enkephalin
EINECS	Contact for details

Quality Control

Our Enkephalin analog is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Our quality commitment supports reproducible and reliable results for your critical studies.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with molecular weight
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in DMSO, acetic acid; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.