Description

1,4-Difluoro-2,3-Dimethoxybenzene is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. Its value lies in its unique substitution pattern, which makes it a versatile precursor for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), liquid crystal materials, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially those requiring fluorinated aromatic cores for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where the difluoro-dimethoxy motif contributes to biological activity.
• Liquid Crystal Materials (LCs): Serves as a fundamental building block for fluorinated liquid crystal compounds used in display technologies.
• Organic Electronic Materials: Employed in the research and production of materials for organic light-emitting diodes (OLEDs) and semiconductors.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create more complex biaryl structures.
• Chemical Research & Development: A valuable reagent for methodological studies and exploring new fluorination chemistry or heterocycle formation.

Basic Information

Product Name	1,4-Difluoro-2,3-Dimethoxybenzene
CAS No.	75626-18-5
Molecular Formula	C8H8F2O2
Molecular Weight	174.14 g/mol
Synonyms	2,3-Dimethoxy-1,4-difluorobenzene; 1,4-Difluoro-2,3-dimethoxybenzene; Benzene, 1,4-difluoro-2,3-dimethoxy-; 2,3-Dimethoxy-p-difluorobenzene; 75626-18-5; 1,4-Difluoro-2,3-dimethoxy-benzene
EINECS	Contact for details

Quality Control

Our 1,4-Difluoro-2,3-Dimethoxybenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.