Description

2,5-Difluoroanisole is a versatile fluorinated aromatic ether, a key building block in advanced organic synthesis. Its value lies in the unique reactivity imparted by the fluorine atoms and methoxy group, enabling precise molecular construction for high-value intermediates. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and liquid crystal material sectors, where it serves as a critical precursor for active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a core component in the synthesis of fluorinated liquid crystals for high-performance displays (LCDs) due to its influence on dielectric anisotropy and viscosity.
• Organic Electronics: Acts as a building block for electron-transport materials and semiconductors in OLEDs and organic photovoltaics.
• Chemical Research & Development: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to create complex, fluorinated aromatic systems.
• Dye and Pigment Intermediate: Used in the synthesis of specialized fluorinated dyes and pigments with enhanced lightfastness and color properties.

Basic Information

Product Name	2,5-Difluoroanisole
CAS No.	75626-17-4
Molecular Formula	C7H6F2O
Molecular Weight	144.12 g/mol
Synonyms	1,4-Difluoro-2-methoxybenzene; 2,5-Difluorophenyl methyl ether; 2-Methoxy-1,4-difluorobenzene; Anisole, 2,5-difluoro-; Benzene, 1,4-difluoro-2-methoxy-; 2,5-DFA
EINECS	Contact for details

Quality Control

Our 2,5-Difluoroanisole is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.