Description

[(3-Methylisoxazol-5-Yl)Methyl]Triphenylphosphonium Chloride is a specialized organophosphorus salt widely used as a key reagent in organic synthesis. This compound is valued for its role as a stable ylide precursor, enabling critical carbon-carbon bond-forming reactions essential for constructing complex molecular architectures. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and advanced agrochemical intermediates.

Application

• Wittig Reaction Reagent: Serves as a crucial precursor for generating stabilized ylides used in the synthesis of alkenes, particularly for introducing the (3-methylisoxazol-5-yl)methyl moiety into target molecules.
• Pharmaceutical Intermediate: Employed in the research and development of novel drug candidates, especially in constructing heterocyclic cores prevalent in modern medicinal chemistry.
• Agrochemical Synthesis: Used in the production pathway for advanced crop protection agents and herbicides that require specific isoxazole-containing structures.
• Material Science Research: Acts as a building block for synthesizing functional organic materials and ligands for catalysis.
• Academic & Process Chemistry: A valuable tool for methodological development and scale-up studies in synthetic organic chemistry laboratories.

Basic Information

Product Name	[(3-Methylisoxazol-5-Yl)Methyl]Triphenylphosphonium Chloride
CAS No.	75624-75-8
Molecular Formula	C24H23ClNO1P
Molecular Weight	407.87 g/mol
Synonyms	(3-Methyl-5-isoxazolylmethyl)triphenylphosphonium chloride; 5-[(Triphenylphosphonio)methyl]-3-methylisoxazole chloride; [(3-Methyl-1,2-oxazol-5-yl)methyl]triphenylphosphanium chloride; Triphenyl[(3-methylisoxazol-5-yl)methyl]phosphonium chloride; Phosphonium, [(3-methyl-5-isoxazolyl)methyl]triphenyl-, chloride; P-[(3-Methyl-5-isoxazolyl)methyl]triphenylphosphonium chloride
EINECS	Contact for details

Quality Control

Our [(3-Methylisoxazol-5-Yl)Methyl]Triphenylphosphonium Chloride is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and NMR for structural confirmation, to ensure consistency and compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.