Description

(R)-5-(2-(Benzyl(4-Phenylbutan-2-Yl)Amino)Acetyl)-2-(Benzyloxy)Benzamide is a chiral, non-racemic organic compound featuring a benzamide core with a complex amine side chain, making it a valuable intermediate for advanced pharmaceutical synthesis. Its defined stereochemistry at the (R)-configured center is critical for applications requiring high enantiomeric purity, such as the development of active pharmaceutical ingredients (APIs) and chiral catalysts. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of potential drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its complex, functionalized structure.
• Chiral Catalyst or Ligand Precursor: The amine functionality can be modified for use in asymmetric synthesis to induce chirality in other molecules.
• Process Chemistry Development: Employed in scaling up synthetic routes for APIs where the (R)-enantiomer is the desired active form.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(R)-5-(2-(Benzyl(4-Phenylbutan-2-Yl)Amino)Acetyl)-2-(Benzyloxy)Benzamide
CAS No.	75615-53-1
Molecular Formula	C33H34N2O3
Molecular Weight	506.64 g/mol
Synonyms	(R)-5-[2-[Benzyl(4-phenylbutan-2-yl)amino]acetyl]-2-(benzyloxy)benzamide; Benzamide, 5-[2-[benzyl(4-phenyl-2-butyl)amino]acetyl]-2-(phenylmethoxy)-, (R)-; (R)-N-{5-[2-(Benzyl{1-methyl-3-phenylpropyl}amino)acetyl]-2-(benzyloxy)phenyl}formamide (tautomer); UNII-7K5P8A5FBR; 7K5P8A5FBR; (R)-enantiomer of 5-(2-(Benzyl(4-Phenylbutan-2-Yl)Amino)Acetyl)-2-(Benzyloxy)Benzamide
EINECS	Contact for details

Quality Control

Our (R)-5-(2-(Benzyl(4-Phenylbutan-2-Yl)Amino)Acetyl)-2-(Benzyloxy)Benzamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, NMR, and mass spectrometry for structural confirmation, to ensure high chemical and chiral purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP guidelines for pharmaceutical intermediates, ensuring traceability and consistency for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is light-sensitive (store away from light). For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.