Description

1,2-Cyclohexanediol, 1-Ethynyl-, cis- (9Ci) is a specialized, high-purity organic compound featuring a unique cis-diol and terminal alkyne functional group. This molecular architecture makes it a valuable chiral building block and intermediate for advanced organic synthesis. It is primarily sought after by research and development chemists in the pharmaceutical and fine chemical industries for applications in asymmetric synthesis, ligand development, and the creation of complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of active pharmaceutical ingredients (APIs), particularly in asymmetric synthesis.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis, including those for transition metal-catalyzed cross-coupling reactions.
• Fine Chemical Production: Serves as a building block for the synthesis of complex, high-value specialty chemicals and agrochemicals.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry and material science research.
• Polymer Modification: Potential use as a monomer or cross-linking agent for creating novel polymers with specific functional properties.

Basic Information

Product Name	1,2-Cyclohexanediol, 1-Ethynyl-, cis- (9Ci)
CAS No.	75476-42-5
Molecular Formula	C8H12O2
Molecular Weight	140.18 g/mol
Synonyms	cis-1-Ethynyl-1,2-cyclohexanediol; (1R,2S)-1-Ethynylcyclohexane-1,2-diol; 1-Ethynyl-cis-1,2-cyclohexanediol; 1,2-Cyclohexanediol, 1-ethynyl-, (1R,2S)-rel-; 1-Ethynylcyclohexane-1,2-diol; cis-1-Ethynylcyclohexane-1,2-diol
EINECS	Contact for details

Quality Control

Our 1,2-Cyclohexanediol, 1-Ethynyl-, cis- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and structural identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C or as indicated on the label. This compound is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.