Description

1,2-Cyclohexanediol, 1-Ethynyl-, trans- (9Ci) is a specialized organic compound featuring a cyclohexane diol backbone with an ethynyl substituent. This unique structure makes it a valuable chiral building block and intermediate for synthesizing complex molecules in advanced research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for applications in asymmetric synthesis and the preparation of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs) and therapeutic candidates.
• Asymmetric Synthesis: Utilized as a building block or ligand precursor in stereoselective reactions to create enantiomerically pure compounds.
• Fine Chemical Synthesis: Serves as a versatile intermediate in the production of specialty chemicals, agrochemicals, and performance materials.
• Academic & Industrial R&D: Employed in research laboratories for methodological development and exploring new chemical spaces in organic chemistry.
• Ligand and Catalyst Development: The diol and ethynyl functional groups provide handles for constructing complex chelating ligands or organocatalysts.
• Material Science Precursor: Potential use in the synthesis of monomers or cross-linkers for specialized polymers and resins.

Basic Information

Product Name	1,2-Cyclohexanediol, 1-Ethynyl-, trans- (9Ci)
CAS No.	75476-41-4
Molecular Formula	C8H12O2
Molecular Weight	140.18 g/mol
Synonyms	trans-1-Ethynyl-1,2-cyclohexanediol; (1R,2R)-1-Ethynylcyclohexane-1,2-diol; (1S,2S)-1-Ethynylcyclohexane-1,2-diol; 1-Ethynyl-trans-1,2-cyclohexanediol; 1,2-Cyclohexanediol, 1-ethynyl-, trans-; Ethynylcyclohexanediol; Chiral Ethynyl Diol Building Block
EINECS	Contact for details

Quality Control

Our 1,2-Cyclohexanediol, 1-Ethynyl-, trans- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and specific parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (enantiomeric excess)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.