Description

1-Propanone, 3-(4-(4-Chlorophenyl)-1-Piperazinyl)-1-(4-Methyl-2-(Methy Lthio)-5-Thiazolyl)-, Hydrochloride, Hydrate (2:2:1) CAS NO 75449-06-8 is a high-purity, complex organic salt with a defined stoichiometry, primarily utilized as a key pharmaceutical intermediate in advanced synthesis. Its value lies in providing a reliable and consistent building block for the research and development of novel therapeutic agents. This compound is essential for pharmaceutical manufacturers and contract research organizations (CROs) engaged in the synthesis of specialized active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, particularly in central nervous system (CNS) and psychiatric therapeutic areas.
• Research & Development (R&D): Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new chemical entities.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a key building block in the production route for complex, target-specific APIs.
• Biochemical Research: Employed as a tool compound in pharmacological assays and receptor binding studies to investigate biological pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP-compliant production of clinical trial materials.

Basic Information

Product Name	1-Propanone, 3-(4-(4-Chlorophenyl)-1-Piperazinyl)-1-(4-Methyl-2-(Methy Lthio)-5-Thiazolyl)-, Hydrochloride, Hydrate (2:2:1)
CAS No.	75449-06-8
Molecular Formula	C18H23ClN4OS2 • HCl • 0.5H2O
Molecular Weight	Contact for details
Synonyms	3-(4-(4-Chlorophenyl)piperazin-1-yl)-1-(4-methyl-2-(methylthio)thiazol-5-yl)propan-1-one hydrochloride hydrate; 3-(4-(p-Chlorophenyl)-1-piperazinyl)-1-(4-methyl-2-(methylthio)-5-thiazolyl)-1-propanone hydrochloride hydrate; Tiospirone Hydrochloride Impurity; Tiospirone Related Compound; Thiazolylpiperazine derivative; CAS 75449-06-8
EINECS	Contact for details

Quality Control

Our 1-Propanone, 3-(4-(4-Chlorophenyl)-1-Piperazinyl)-1-(4-Methyl-2-(Methy Lthio)-5-Thiazolyl)-, Hydrochloride, Hydrate (2:2:1) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for use as a pharmaceutical intermediate. Comprehensive Certificates of Analysis (COA) documenting all critical quality attributes are available upon request to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.