Description

9-Tyr-β-Msh (9-18) CAS NO 75389-13-8 is a synthetic peptide fragment derived from the β-melanocyte-stimulating hormone (β-MSH) sequence. This compound is of significant interest in biochemical and pharmacological research due to its role in studying melanocortin receptor interactions and related signaling pathways. It is primarily utilized by research institutions, pharmaceutical developers, and biotechnology companies engaged in neuroscience, endocrinology, and peptide-based drug discovery.

Application

• Biochemical Research: Used as a reference standard and tool compound for studying the structure-activity relationships (SAR) of melanocortin peptides.
• Pharmacological Studies: Employed in in vitro and in vivo assays to investigate binding affinity and functional activity at melanocortin receptors (MC1R, MC3R, MC4R, MC5R).
• Neuroscience Research: Facilitates exploration of the role of melanocortin systems in feeding behavior, energy homeostasis, and inflammatory responses.
• Drug Discovery: Serves as a key intermediate or analog in the development of novel peptide therapeutics targeting metabolic and neurological disorders.
• Academic Research: A critical reagent for university and institutional labs focusing on peptide chemistry, hormone biology, and receptor pharmacology.

Basic Information

Product Name	9-Tyr-β-Msh (9-18)
CAS No.	75389-13-8
Molecular Formula	C58H85N17O16S
Molecular Weight	1260.5 g/mol
Synonyms	β-MSH (9-18); β-Melanocyte Stimulating Hormone (9-18); Tyr-β-MSH (9-18); H-Tyr-Val-Met-Gly-His-Phe-Arg-Trp-Asp-Arg-Phe-Gly-OH (Disulfide bridge: Cys2-Cys8); L-Tyrosyl-L-valyl-L-methionylglycyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophyl-L-α-aspartyl-L-arginyl-L-phenylalanylglycine; Melanotropin beta (9-18); β-MSH fragment 9-18
EINECS	Contact for details

Quality Control

Our 9-Tyr-β-Msh (9-18) is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and MS for identity confirmation, to ensure it meets the high standards required for research applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Analysis	Within ± 10% of theoretical
Solubility	Soluble in water, dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.