Description

2-Methyl-4-Oxo-4-(3'-Fluorophenyl)Butyric Acid is a high-purity fluorinated organic acid derivative, serving as a critical chiral building block and advanced pharmaceutical intermediate. Its value lies in the precise structural features that enable the synthesis of complex, biologically active molecules, particularly in the development of new active pharmaceutical ingredients (APIs). This compound is essential for research and manufacturing chemists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for complex synthetic routes.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel APIs, especially for central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and development of advanced fluorinated pesticides and herbicides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Fine Chemical Production: Serves as a versatile precursor for the manufacture of complex fluorinated organic compounds used in material science and specialty chemistry.
• Research & Development: A valuable tool in medicinal chemistry for structure-activity relationship (SAR) studies and the exploration of new chemical entities.
• Custom Synthesis: Employed as a starting material for contract research organizations (CROs) and CDMOs for client-specific molecule development.

Basic Information

Product Name	2-Methyl-4-Oxo-4-(3'-Fluorophenyl)Butyric Acid
CAS No.	75380-94-8
Molecular Formula	C11H11FO3
Molecular Weight	210.20 g/mol
Synonyms	4-(3-Fluorophenyl)-2-methyl-4-oxobutanoic acid; 3'-Fluoro-2-methyl-4-oxo-4-phenylbutyric acid; (RS)-2-Methyl-4-oxo-4-(3-fluorophenyl)butanoic acid; 4-Oxo-4-(3-fluorophenyl)-2-methylbutyric acid; 75380-94-8; Butanoic acid, 4-(3-fluorophenyl)-2-methyl-4-oxo-; 2-Methyl-4-oxo-4-(m-fluorophenyl)butyric acid
EINECS	Contact for details

Quality Control

Our 2-Methyl-4-Oxo-4-(3'-Fluorophenyl)Butyric Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and materials for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. Due to its nature as a strong acid/organic solvent, handle with appropriate personal protective equipment in a fume hood or well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.