Description

4-Bromo-3,5-Dimethyl-Benzonitrile is a versatile halogenated aromatic nitrile building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both a bromine substituent and a nitrile group on a dimethylated benzene ring, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors. Its utility lies in enabling key transformations such as cross-coupling reactions and cyano group conversions, which are fundamental to developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the bromine atom serves as a handle for further functionalization.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and as a building block for functional materials.
• Organic Electronic Materials: Serves as a monomer or intermediate in the synthesis of conjugated polymers and small molecules for applications in OLEDs and organic photovoltaics.
• Chemical Research & Development: A valuable reagent for method development in cross-coupling chemistry (e.g., Suzuki, Buchwald-Hartwig amination) and other metal-catalyzed processes.
• Dye and Pigment Intermediate: Utilized in the synthesis of complex aromatic dyes and high-performance pigments.

Basic Information

Item	Details
Product Name	4-Bromo-3,5-Dimethyl-Benzonitrile
CAS No.	75344-77-3
Molecular Formula	C9H8BrN
Molecular Weight	210.07 g/mol
Synonyms	3,5-Dimethyl-4-bromobenzonitrile; 4-Bromo-3,5-dimethylbenzonitrile; 4-Bromo-3,5-dimethyl-benzonitrile; 4-Bromo-3,5-dimethylbenzenecarbonitrile; 4-Bromo-3,5-dimethylphenyl cyanide; 75344-77-3; Benzonitrile, 4-bromo-3,5-dimethyl-
EINECS	Contact for details

Quality Control

Our 4-Bromo-3,5-Dimethyl-Benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and industrial-scale synthesis. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles, typically determined by HPLC, GC, NMR, and IR spectroscopy. Our quality commitment ensures reliable performance in your most sensitive synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.