Description

Nemonapride CAS NO 75272-39-8 is a high-purity benzamide derivative and a potent, selective dopamine D2 and D3 receptor antagonist. This compound is of significant interest in pharmaceutical research and development due to its specific neurochemical activity. It serves as a critical reference standard and active pharmaceutical ingredient (API) intermediate for neuroscience studies and the development of novel antipsychotic agents.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in drug manufacturing.
• Neuroscience Research: Employed in preclinical studies to investigate dopamine receptor pharmacology, signal transduction pathways, and behavioral models.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a key synthetic building block in the production of antipsychotic medications.
• Biochemical Assay Development: Utilized in high-throughput screening (HTS) and in vitro binding assays to identify and characterize new receptor ligands.
• Metabolite and Impurity Standard: Essential for the identification and quantification of related substances in compliance with ICH guidelines.

Basic Information

Product Name	Nemonapride
CAS No.	75272-39-8
Molecular Formula	C21H26ClN3O2
Molecular Weight	387.91 g/mol
Synonyms	YM-09151-2; Emonapride; (3S)-N-[(1-Allyl-2-pyrrolidinyl)methyl]-5-chloro-2-methoxy-4-methylaminobenzamide; 5-Chloro-2-methoxy-4-(methylamino)-N-[(2S)-1-(2-propen-1-yl)-2-pyrrolidinyl]methyl]benzamide; YM 09151-2; Nemonapridum; Lexir
EINECS	Contact for details

Quality Control

Our Nemonapride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and MS, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) that detail all test results, ensuring compliance with research and pharmaceutical intermediate standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.